Dengue IgG/IgM is a rapid immunochromatographic test for the qualitative differential detection of IgG and IgM antibodies in human serum/plasma/whole blood. Dengue virus belongs to Flaviviridae family, common in tropical and sub-tropical regions, which is found in four distinct serotypes (1, 2, 3 and 4). Dengue fever is transmitted by mosquitoes, of the species Aedes aegypti and Aedes albopictus. Primary dengue infection results mostly in a self-limiting mild to high fever, while secondary infection is more common and potentially fatal resulting in severe conditions like Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS). The following table gives the duration for detectable rise in NS1 antigen, IgG and IgM antibodies in blood in cases of primary and secondary infections:
Ab Primary Infection Secondary Infection
IgM 5-10 days 4-5 days
IgG 14 Days till life time 1-2 days


The dengue IgG/IgM device can simultaneously detect and differentiate IgG and IgM antibodies to dengue virus in human serum, plasma or whole blood. This test can also detect all 4 dengue serotypes by using a mixture of recombinant dengue envelope proteins. The device consists of a membrane with 3 pre-coated lines: a test line “G” of monoclonal anti- human IgG, a test line “M” of monoclonal anti-human IgM and a control line “C” of goat anti-rabbit IgG. The sample moves along the membrane, complexing with the recombinant dengue virus envelope protein-gold conjugate. Pink/purple “G” and “M” lines will be visible in the result window if there are enough IgG and/or IgM antibodies respectively to dengue virus in the sample. Absence of either of the test lines indicates a negative result.

The unreacted complexes move even further and are immobilized at the control region “C” and form a pink/purple colored band. Absence of control line “C” indicates an INVALID TEST.
Instructions for Use: